Technology Appraisal Guidance No. 123
Source: National Institute for Health and Clinical Excellence
- Varenicline is recommended within its licensed indications as an option for smokers who have expressed a desire to quit smoking.
- Varenicline should normally be prescribed only as part of a programme of behavioural support.
The guidance shown above constitutes Section 1 of the full document. A copy of the full document and a summary of the evidence is available on the Internet at
An abridged version of this guidance (a 'quick reference guide') is also available. Printed copies of the quick reference guide can be obtained by ing 0845 003 7783 or emailingand quoting reference number N1284. It is also available on the Internet at
This guidance represents the view of the Institute which was arrived at after careful consideration of the available evidence. Health professionals are expected to fully take it into account when exercising their clinical judgement. This guidance does not, however, override the individual responsibility of health professionals to make appropriate decisions in the circumstances of the individual patient, in consultation with the patient and/or guardian or carer.
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Enquiries concerning the guidance should be addressed to: National Institute for Health and Clinical Excellence, MidCity Place, 71 High Holborn, London WC1V 6NA. email:
Varenicline for Smoking Cessation.
Issue Date: July 2007
Review Date: May 2010