Technology Appraisal Guidance No. 233
Source: National Institute for Health and Care Excellence
NOTE: This guidance has been replaced by NICE technology appraisal guidance 383.
1.1 Golimumab is recommended as an option for the treatment of
severe, active ankylosing spondylitis in adults only if:
- it is used as described for adalimumab and etanercept in ‘Adalimumab, etanercept and infliximab for ankylosing spondylitis’ (NICE technology appraisal guidance 143) and
- the manufacturer provides the 100 mg dose of golimumab at the same cost as the 50 mg dose in accordance with the patient access scheme.
1.2 People currently receiving golimumab for the treatment of severe, active ankylosing spondylitis who do not fulfil the criteria for treatment with adalimumab and etanercept described in NICE technology appraisal guidance 143 should have the option to continue golimumab until they and their clinician consider it appropriate to stop.
The guidance shown above constitutes Section 1 of the full document. A copy of the full document and a summary of the evidence is available on the Internet at
An abridged version of this guidance (a 'quick reference guide') is also available. Printed copies of the quick reference guide can be obtained by ing 0845 003 7783 or emailingand quoting reference number N2583. It is also available on the Internet at
This guidance represents the view of the Institute which was arrived at after careful consideration of the available evidence. Health professionals are expected to fully take it into account when exercising their clinical judgement. This guidance does not, however, override the individual responsibility of health professionals to make appropriate decisions in the circumstances of the individual patient, in consultation with the patient and/or guardian or carer.
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Enquiries concerning the guidance should be addressed to: National Institute for Health and Care Excellence, MidCity Place, 71 High Holborn, London WC1V 6NA. email:
Golimumab for the Treatment of Ankylosing Spondylitis.
Issue Date: August 2011