Technology Appraisal Guidance No. 81
Source: National Institute for Health and Care Excellence
This appraisal relates to the frequency of application of topical corticosteroids in the treatment of atopic eczema. It does not include the use of topical agents that combine corticosteroids with other active agents (for example, antimicrobials or salicylic acid).
1.1 It is recommended that topical corticosteroids for atopic eczema should be prescribed for application only once or twice daily.
1.2 It is recommended that where more than one alternative topical corticosteroid is considered clinically appropriate within a potency class, the drug with the lowest acquisition cost should be prescribed, taking into account pack size and frequency of application.
The guidance shown above constitutes Section 1 of the full document. A copy of the full document and a summary of the evidence is available on the Internet at
Copies of the document can also be obtained by ing 0845 003 7783 or emailingand quoting reference number N0616.
This guidance represents the view of the Institute which was arrived at after careful consideration of the available evidence. Health professionals are expected to fully take it into account when exercising their clinical judgement. This guidance does not, however, override the individual responsibility of health professionals to make appropriate decisions in the circumstances of the individual patient, in consultation with the patient and/or guardian or carer.
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Frequency of application of topical corticosteroids for atopic eczema.
Issue Date: August 2004
Review Date: July 2007